knex

A batteries-included SQL query & schema builder for PostgresSQL, MySQL, CockroachDB, MSSQL and SQLite3

sequelize

Sequelize is a promise-based Node.js ORM tool for Postgres, MySQL, MariaDB, SQLite, Microsoft SQL Server, Amazon Redshift and Snowflake’s Data Cloud. It features solid transaction support, relations, eager and lazy loading, read replication and more.