epoll
A low-level Node.js binding for the Linux epoll API
onoff
GPIO access and interrupt detection with Node.js
rpio
High performance GPIO/i2c/PWM/SPI module for Raspberry Pi, Orange Pi, Banana Pi
pigpio
Fast GPIO, PWM, servo control, state change notification, and interrupt handling on the Raspberry Pi
mraa
IO library that helps you use I2c, SPI, gpio, uart, pwm, analog inputs (aio) and more on a number of platforms such as the Intel galileo, the Intel edison and others