knex
A batteries-included SQL query & schema builder for PostgresSQL, MySQL, CockroachDB, MSSQL and SQLite3
@prisma/client
Prisma Client is an auto-generated, type-safe and modern JavaScript/TypeScript ORM for Node.js that's tailored to your data. Supports PostgreSQL, CockroachDB, MySQL, MariaDB, SQL Server, SQLite & MongoDB databases.
sql.js
SQLite library with support for opening and writing databases, prepared statements, and more. This SQLite library is in pure javascript (compiled with emscripten).
rxdb
A local-first realtime NoSQL Database for JavaScript applications - https://rxdb.info/